Diazepam is a benzodiazepine class of drug with anticonvulsant, anxiolytic, sedative, muscle relaxant, and amnestic properties. It acts by enhancing the activity of certain neurotransmitters in the brain. Benzodiazepines have a minimal role in insomnia and it is used for the short-term treatment of insomnia associated with anxiety.
Mechanism of Action of Drug
The exact sites and mode of action of the benzodiazepines have not been clear, but the drugs acted by mediated through the inhibitory neurotransmitter γ-aminobutyric acid (GABA). The drug acts at the limbic, thalamic, and hypothalamic levels of the CNS, producing anxiolytic, sedative, hypnotic, skeletal muscle relaxant, and anticonvulsant effects.
Uses Diazepam 10 mg tablets
Diazepam 10 mg is used in the short-term treatment of severe sleeping disorders, as a hypnotic in the short-term management of insomnia, as a sedative and premedical, as an anticonvulsant (particularly in managing status epilepticus and febrile convulsions), in treating of muscle spasm and managing withdrawal symptoms.
Diazepam medicine is prescribed to treat sleeping disorders, muscle spasms, and symptoms of alcohol withdrawal. Sometimes, it can also be used along with other medicines to manage seizures. It’s also available in the injection form as well as a rectal gel and nasal spray that are used only for seizure control. Diazepam isn’t meant to be taken long-term because using it can raise the risk of dependence. Some common side effects of diazepam include sleepiness, dizziness, and muscle weakness.
Contradictions
- Patients who are hypersensitive to other benzodiazepines class of drugs, this drug, or any ingredient in the formulation or component of the container.
- Severe respiratory insufficiency.
- Severe hepatic impairment.
- Sleep apnea syndrome.
- Myasthenia gravis.
- Narrow-angle glaucoma
Diazepam Side Effects
Diazepam can slow or stop breathing, especially if you have recently used an opioid medication or alcohol. A person caring for you should seek emergency medical attention if you have difficulty in breathing with long pauses, blue-colored lips, or if you find it hard to wake up.
Consult with the doctor if you have sudden changes in mood or behavior, including new or worse depression or anxiety, trouble sleeping, or if you feel impulsive, irritable, agitated, hostile, aggressive, restless, more talkative, or have thoughts about suicide or hurting yourself.
- severe drowsiness or dizziness
- trouble breathing
- confusion, paranoia; or
- New or worsening seizures
- Common diazepam side effects may include
- drowsiness
- feeling tired
- muscle weakness
- Problems with balance or muscle movement
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